AnatomyBeginner2D simulation~12 min

Digestive System

A sandwich cannot pass into your blood. Before your cells can use it, it must be broken down into molecules small enough to cross the gut wall. Pick a meal and follow it through about 9 metres of digestive tract, watching each nutrient being taken apart and absorbed.

Mouth Click an organ to learn about it
Choose a meal

Changing the meal starts a new one. Fatty meals stay longer in the stomach.

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The food is in the
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Time since eating (typical)
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Energy absorbed so far
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How to use this simulator

  1. Choose a meal. The food starts in the mouth and moves on by itself; use Speed to go faster or slower.
  2. Watch the bars: the solid part is intact food, the faded part has been broken down, and the green part has been absorbed.
  3. Highlighted enzyme labels show which juices are working right now. Read the panel text for what is happening.
  4. Compare meals: when does protein start being digested? How long does olive oil stay in the stomach?
  5. Click any organ to learn about it. When the meal finishes, press Start to eat it again.

What digestion does

Food contains large molecules such as starch, proteins and fats. Digestion breaks them into small, soluble molecules that can be absorbed into the blood: glucose, amino acids,fatty acids and glycerol. It happens in two ways. Mechanical digestion (chewing and the stomach’s churning) breaks food into smaller pieces, giving enzymes more surface to work on.Chemical digestion uses enzymes to break chemical bonds.

The journey, organ by organ

  • Mouth: teeth chew; saliva moistens food into a soft ball called a bolus and starts digesting starch.
  • Oesophagus: peristalsis carries the bolus to the stomach in about 5–10 seconds.
  • Stomach: muscular churning mixes food with acid and pepsin, turning it into a soupy liquid called chyme. Food stays here about 2–4 hours, longer for fatty meals.
  • Small intestine: about 6 m long. Most digestion and nearly all absorption of nutrients happen here, over about 3–5 hours.
  • Large intestine: about 1.5 m long. It absorbs water and salts over 10–40 hours, and its bacteria ferment some fibre.
  • Rectum and anus: the remains (faeces) are stored and then egested.

Digestive enzymes

EnzymeMade inWorks inBreaks down → into
AmylaseSalivary glands, pancreasMouth, small intestineStarch → maltose (then glucose)
PepsinStomachStomach (acidic)Proteins → peptides
Trypsin and peptidasesPancreas, intestine wallSmall intestinePeptides → amino acids
LipasePancreasSmall intestineFats → fatty acids + glycerol

Each enzyme has an optimum pH: pepsin works best in the strongly acidic stomach (about pH 2), while pancreatic enzymes need the slightly alkaline conditions of the small intestine, created by bicarbonate from the pancreas.

Absorption and villi

The inner wall of the small intestine is folded and covered in millions of finger-like villi, each covered in even smaller microvilli. Together they give a surface area of about 30 m². Each villus has a thin wall and a rich network of capillaries, which take in glucose and amino acids, and a lymph vessel called alacteal, which takes in most digested fats. Absorbed nutrients travel first to the liver.

Liver, gallbladder and pancreas

Food never passes through these accessory organs, but the tract could not work without them. Theliver makes bile, which the gallbladder stores and releases after a meal. Bileemulsifies fats into tiny droplets. The pancreas releases a juice full of enzymes into the small intestine, and separately makes the hormones insulin and glucagon that control blood sugar.

Key terms

Bolus / chyme
A swallowed ball of chewed food / the acidic liquid that leaves the stomach.
Peristalsis
Waves of muscle contraction that push food along the gut.
Absorption / egestion
Taking digested molecules into the blood / removing undigested waste from the body.

Common misconceptions

  • “Most digestion happens in the stomach.” The stomach starts protein digestion, but most digestion and absorption happen in the small intestine.
  • “Bile is an enzyme.” Bile contains no enzymes; it physically breaks fat into droplets.
  • “Fibre is useless.” It is not digested, but it feeds gut bacteria and keeps food moving.

Educational model only. Times and percentages are typical textbook values; real digestion varies a great deal between people and meals. This simulator is not medical or dietary advice. If you have symptoms or questions about your digestion or diet, speak to a qualified healthcare professional. See oureducational and medical disclaimer.

Key takeaways

  • Digestion turns large food molecules into small soluble ones the body can absorb.
  • Amylase digests starch, proteases (pepsin, trypsin) digest proteins, and lipase digests fats.
  • Most absorption happens through the villi of the small intestine.
  • The large intestine absorbs water; fibre and waste leave as faeces.

Model note: the diagram is simplified, and the meal is shown as a single lump moving through. In reality food leaves the stomach gradually in small squirts, and time in the large intestine varies widely.

Knowledge check

Digestive System: test your understanding

Answer each question to get instant feedback and an explanation. Use the simulator to check your thinking.

8 questions4 basic3 intermediate1 advanced

0 of 8 answered

  1. Q1BasicWhere are most nutrients absorbed into the blood?
    Show answer

    Answer: B. Small intestine

    The small intestine is about 6 m long and lined with villi, giving a huge surface area for absorbing sugars, amino acids and fatty acids.

  2. Q2BasicWhich enzyme starts digesting starch in the mouth?
    Show answer

    Answer: C. Amylase

    Salivary amylase begins breaking starch into smaller sugars (maltose) while you chew.

  3. Q3BasicWhat moves food along the oesophagus and intestines?
    Show answer

    Answer: B. Peristalsis: waves of muscle contraction

    Rings of smooth muscle contract in waves behind the food, squeezing it forward. That is why astronauts can still swallow in space.

  4. Q4IntermediateWhat is the job of bile?
    Show answer

    Answer: B. It emulsifies fats into small droplets, giving lipase a larger surface to work on

    Bile is made by the liver and stored in the gallbladder. It contains no enzymes, but breaking fat into droplets speeds up digestion by lipase. It also helps neutralise stomach acid.

  5. Q5IntermediateWhy does the stomach contain hydrochloric acid?
    Show answer

    Answer: B. To kill most microbes in food and provide the low pH that pepsin needs

    Pepsin works best at about pH 2. The acid also destroys many harmful bacteria swallowed with food.

  6. Q6IntermediateIn the simulator, the fibre bar barely changes until the large intestine. Why?
    Show answer

    Answer: B. Human enzymes cannot digest fibre; some is fermented later by gut bacteria

    We lack enzymes to break down cellulose and most other fibres. Bacteria in the colon ferment part of it; the rest adds bulk to faeces.

  7. Q7BasicWhich pair correctly matches a nutrient with the small molecules it is digested into?
    Show answer

    Answer: C. Starch → glucose

    Starch → glucose (via maltose), proteins → amino acids, fats → fatty acids and glycerol.

  8. Q8AdvancedChoose “Olive oil” and compare the time in the stomach with “Bread”. What does this show?
    Show answer

    Answer: B. Fat slows stomach emptying, so fatty meals stay in the stomach longer

    Hormones released when fat reaches the duodenum slow stomach emptying, giving bile and lipase time to work. This is why fatty meals feel filling.

References and further reading

  1. Betts, J. G., et al. (2022). Anatomy and Physiology 2e, Section 23.1: Overview of the Digestive System. OpenStax. openstax.org (opens in a new tab)
  2. Betts, J. G., et al. (2022). Anatomy and Physiology 2e, Section 23.7: Chemical Digestion and Absorption: A Closer Look. OpenStax. openstax.org (opens in a new tab)
  3. Helander, H. F., & Fändriks, L. (2014). Surface area of the digestive tract – revisited. Scandinavian Journal of Gastroenterology, 49(6), 681–689.
  4. National Institute of Diabetes and Digestive and Kidney Diseases. Your Digestive System & How It Works. niddk.nih.gov (opens in a new tab)

This page is an educational model, not medical advice. Found an error? Let us know. See our educational disclaimer.